FARM1130 – Pharmaceutically Based Organic Chemistry
Course description
Schedule, syllabus and examination date
Course content
This course will provide students in pharmacy a solid foundation in organic chemistry where relevant pharmaceutical topics will be applied to illustrate organic chemistry. The course will also give the students the necessary knowledge to participate and understand the pharmacy curriculum in later courses, such as biochemistry, medicinal chemistry, pharmacognosy, drug analysis and pharmaceutics. In this course examples from medicinal chemistry and pharmacognosy will be used to acquire knowledge in organic chemistry.
Learning outcome
After completing the course:
- you will have a solid foundation and knowledge in stereochemistry and the related terms and definitions, and you can apply these to active pharmaceutical ingredients in drugs and natural products.
- you will have a solid knowledge and understanding of the pharmaceutically most relevant organic reactions and their mechanism. Emphasis will be on elimination reactions, electrophilic aromatic substitution reactions, carbonyl based reactions and condensation reactions.
- you will have solid knowledge on aromatic compounds, aliphatic compounds and heterocyclic compounds, but also knowledge about the most central reactions and the mechanisms of the compound classes.
- you will have knowledge on the pharmaceutical most relevant substitutions reactions, nucleophilic addition reactions and oxidation/reduction reactions.
- you will also learn and master some relevant techniques used in pharmaceutical laboratory practice and be able to structurally elucidate some chemical simple active pharmaceutical ingredients in drugs and natural products, perform analysis and present results from laboratory exercises.
- you can evaluate the results of simple experiments.
Admission to the course
The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.
Pregnant and breastfeeding:?For safety reasons, pregnant and breastfeeding women can not follow the course because chemicals used in laboratory exercises may be harmful to the fetus/child. No exemption or facilitation of the laboratory exercises is granted as these must be approved to fulfill the learning outcome of the course. For more information contact the Study administration at the Department of Pharmacy.
Formal prerequisite knowledge
- Approved the compulsory parts of FARM1100 – Pharmaceutical Chemistry
- Passed the compulsory HSE courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.
Course exemption: Laws and regulations describing the overall learning outcome regulate the Pharmacy Programme. Exemptions are only granted if all learning outcomes in the course are covered.?
Recommended previous knowledge
Overlapping courses
- 9 credits overlap with FRM1010 – Pharmaceutical Chemistry, Part II (discontinued).
- 9 credits overlap with KJM1111 – Organic Chemistry I.
- 9 credits overlap with KJM1110 – Organic chemistry I (continued).
Teaching
Lectures and student-activating teaching activities, including flipped classroom, laboratory work and student led colloquiums.?
- 30 hours of lectures
- 8 hours of flipped classroom
- 22 hours of student led colloquiums
- 40 hours of laboratory work (five laboratory exercises and submission of five laboratory journals) - compulsory
- 5 hours laboratory lectures - compulsory
Compulsory participation in the course must be completed and compulsory submissions must be approved in order to take the exam.
Read more about what applies in the event of absence from compulsory activities.
As?the?teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance. Read about your insurance cover as a student.
Access to teaching:?A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.
Completed and approved compulsory instruction and coursework are valid for 3 years.
Examination
Final written exam, which counts 100 % towards the finale grade.
Requirements for taking the exam:
- the five laboratory exercises must be conducted, and the five associated laboratory lectures must be attended
- the five laboratory journals must be approved within the given deadlines
Withdrawal from an examination:?It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt.
It will also be counted as one of the three?attempts to sit the exam for this course, if you sit the exam for one of the following courses:
- FRM1010 – Pharmaceutical Chemistry, Part II (discontinued)
- KJM1110 – Organic chemistry I (continued)
- KJM1111 – Organic Chemistry I
Examination support material
You will have access to a calculator in Inspera during exam.
If the resit/postponed exam is held orally, an approved calculator, Casio FX-991EX, will be handed out at the beginning of the exam.
Molecular building kit without manual is accepted.
Language of examination
The examination text is given in Norwegian. You may submit your response in Norwegian, Swedish or Danish.
Grading scale
Grades are awarded on a scale from A to F, where A is the best grade and F?is a fail. Read more about the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more:
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.