Course content

Biological sequence databases. Parwise and multiple sequence alignments, analysis of genomic DNA sequences, protein modeling, Gene Ontology, RNA sequencing, Introduction to programming.

Learning outcome

An understanding of how a comparison of biological sequences can give information on the function and evolution of the sequences. How algorithms for optimal pairwise sequence alignments and for database searches work. A knowledge of tools for homology-based modeling of three-dimensional protein structures. RNA sequencing: Principle and analysis of the results. Knowledge about the use of simple programming to construct and modify computer programs for bioinformatical analyses.

Admission

Students who are admitted to study programmes at UiO must each semester register which courses and exams they wish to sign up for in Studentweb.

If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures.

Prerequisites

Formal prerequisite knowledge

In addition to fulfilling the Higher Education Entrance Qualification, applicants have to meet the following special admission requirements:

  • Mathematics R1 (or Mathematics S1 and S2) + R2

And in addition one of these:

  • Physics (1+2)
  • Chemistry (1+2)
  • Biology (1+2)
  • Information technology (1+2)
  • Geosciences (1+2)
  • Technology and theories of research (1+2)

The special admission requirements may also be covered by equivalent studies from Norwegian upper secondary school or by other equivalent studies (in Norwegian).

MBV1030 – General biochemistry (discontinued) or corresponding. MBV2010 – Molecular biology (continued) or corresponding (from 2008).

Recommended previous knowledge

MAT1000 – Mathematics for applications I (discontinued). MBV2010 – Molecular biology (continued) (prerequisite from 2008).

Overlapping courses

8 credits overlap with BIOS3010 – Bioinformatics

Teaching

Lectures (34 hours), work in PC-lab (about 60 hours).

Examination

Written exam, 3 hours, in June. Allowed examination aids: None. Letter grading.

This subject offer new examination in the beginning of the subsequent term for candidates who withdraw during an ordinary examination or fail an ordinary examination. More information about new examination can be found on the faculty's site.

Explanations and appeals

Evaluation

The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.

Facts about this course

Credits
10
Level
Bachelor
Teaching
Every spring
Examination
Every spring
Teaching language
Norwegian (English on request)