FARM5210 – Novel Drug Delivery Systems (NDDS)
Course description
Course content
Novel drug delivery systems (NDDS) include formulations, delivery systems and technology required for site-specific drug delivery in order to optimize pharmacological effects and reduce side effects. The course will focus on development of NDDS and includes both small molecular drugs and biomolecules. Regulatory aspects related to the selected devices will be discussed.
Learning outcome
After completing the course:
- you will have deep knowledge about the application of nanoparticles, bio conjugates, gels, and implants in drug delivery. Further, you will have a deep knowledge about novel technologies (e.g. theranostics, photochemical internalization) in drug targeting and in delivery of biomolecular drugs.
- you will have deep knowledge about in vitro challenges (e.g. drug load, solubility, stability, release profile) related to NDDS.
- You will have deep knowledge about in vivo challenges (e.g. biological barriers, physiological properties at the administration site, side effects, toxicology) related to NDDS.
- you will be able to discuss regulatory issues related to "quality and safety" upon application of NDDS.
- you will be able to work in a team, and prepare and present an overview on approaches for development of drug delivery systems for specific APIs.
- you will be able to communicate and discuss drug formulation aspects in a scientific forum.
Admission to the course
The course is mainly open to students who have been admitted to the 5-year Master`s Programme in Pharmacy at the Department?of Pharmacy, University of Oslo. In the event that space is available, other master`s level students may apply. Knowledge in relevant subject area corresponding to the content of Semester 1 through 7 at the department’s Master`s Programme in Pharmacy is required. For more information, please contact the Study Administration at the Department of Pharmacy, studieinfo@farmasi.uio.no.
Formal prerequisite knowledge
Passed the exam in:
- FARM1100 – Pharmaceutical Chemistry
- FARM1110 – Pharmacology, Physiology and Cell Biology 1
- FARM1120 – Social Pharmacy
- FARM1130 – Pharmaceutically Based Organic Chemistry
- FARM1140 – Pharmacology, Physiology and Cell Biology 2
- FARM1150 – Pharmaceutical Based Biochemistry
- FARM2100 – Medicinal Chemistry
- FARM2110 – Pharmacotherapy 1
- FARM2120 – Pharmaceutics and Biopharmaceutics
- FARM2130 – Pharmaceutical Analytical Chemistry
- FARM2140 – Pharmaceutical Microbiology
- FARM2150 – Formulation of Drugs and Quality Assurance in Drug Production
- FARM3100 – Pharmacognosy
- FARM3110 – Pharmacotherapy 2
- FARM3120 – Medicine Use and Public Health
- FARM3130 – Advanced Pharmacy Practice Experience (APPE)
- the compulsory HMS-courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.
Approved the compulsory parts of:
- FARM4100 – Personalised Drug Therapy
- FARM4110 – Comprehensive Biopharmacy and Formulation Technology
- FARM4120 – Drug Development
Formal prerequisite knowledge for students admitted to Studiel?p for farmas?yter med mastergrad fra land utenfor EU/E?S:
- FARM4910K – Farmakoterapi og samfunnsfarmasi med fokus p? norske terapitradisjoner og norske forhold
- FARM4920K – Fra virkestoff til ferdig formulering med fokus p? avanserte legemiddelformer
- FARM4930K – Kvalitetssikring ved produksjon og klinisk utpr?vning av legemidler
- approved the compulsory HMS-courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.
For students admitted to the 5-year Master`s Programme in Pharmacy until and including 2016 and who have been transferred from the old study plan, separate formal prerequisite knowledge apply. These are in professional compliance with the formal prerequisite knowledge that apply to the course, but may be replaced by courses from the old study plan, as well as transitional courses. Students on transitional arrangements may contact the study administration for a complete overview of the formal prerequisite knowledge required.
Recommended previous knowledge
Overlapping courses
- 10 credits overlap with FRM5530 – Drug Formulation, Drug Targeting (discontinued).
Teaching
- 2 hours introduction (compulsory)
- 4 hours team work under supervision
- 15 hours team work in combination with flipped classroom to prepare mini lectures and poster
- 4 hours mini lectures (compulsory, pass/fail evaluation)
- 2 hours poster presentation (compulsory, pass/fail evaluation)
- 3 hours visit to pharmaceutical industry or similar (compulsory)
There is a compulsory attendance for the first information lecture. Students who do not meet are expected to have withdrawn from the course unless they have notified a valid due date to the Study Administration,?studieinfo@farmasi.uio.no.
Compulsory participation in the course must be completed and compulsory submissions must be approved to pass the exam.
Read more about what applies in the event of absence from compulsory activities.
As?the?teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance. Read about your insurance cover as a student.
Access to teaching: A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.
Compulsory participation and approved assignments are valid for 3 years.
The course may be cancelled, if the number of enrolled students are low.
Examination
Final written exam, which counts 100 % towards the finale grade.?
Mini lectures, poster preparation and -presentation should be approved prior to the exam.
It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses: FRM5530 – Drug Formulation, Drug Targeting (discontinued)
Examination support material
Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam. You may not use your own calculator on the exam.
Language of examination
The examination text is given in Norwegian. You may submit your response in Norwegian, Swedish or Danish. English on request.
Grading scale
Grades are awarded on a scale from A to F, where A is the best grade and F?is a fail. Read more about the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more:
More about examinations at UiO
- Use of sources and citations
- Special exam arrangements due to individual needs
- Withdrawal from an exam
- Illness at exams / postponed exams
- Explanation of grades and appeals
- Resitting an exam
- Cheating/attempted cheating
You will find further guides and resources at the web page on examinations at UiO.